AGEING

(Redirected from Aging)
The effects of aging on a human face

An elderly woman

'Ageing' or 'aging' is the process of systems' deterioration with time. This article focuses on the social, cognitive, cultural, and economic effects of ageing. The biology of ageing is treated in detail in senescence. Ageing is an important part of all human societies reflecting the biological changes that occur, but also reflecting cultural and societal conventions. Age is usually measured in full years (except for young children, where this downward rounding would be too crude) and a person's birthday is often an important event.
The issue of an ageing population, where the average age of a society is higher now due to higher standards of living is increasingly important in many nations of the world. The societal effects of age are great. Young people tend to commit most crimes, they are more likely to push for political and social change, to develop and adopt new technologies, and to need education. Older people have different requirements from society and government as opposed to young people, and frequently differing values as well. Older people are also far more likely to vote, and in many countries the young are forbidden from voting, and thus the aged have comparatively more political influence.

Contents
Senescence
Dividing the lifespan
Cultural variations
Society
Legal
Economics and marketing
Impact of ageing on health care demand
Effects
Cognitive
Societal ageing
Emotional
Successful ageing
Theories of aging
Biological theories
Measure of age
See also
Notes
Further reading
References

Senescence


Main articles: Senescence

In biology, ''senescence'' is the state or process of ageing. ''Cellular senescence'' is a phenomenon where isolated cells demonstrate a limited ability to divide in culture (the "Hayflick Limit," discovered by Leonard Hayflick in 1965), while ''Organismal senescence'' is the ageing of organisms.
A map showing median age figures for 2001

Ageing is believed to have evolved because of the increasingly smaller probability of an organism still being alive at older age, due to predation and accidents, both of which may be random and age-invariant. It is thought that strategies which result in a higher reproductive rate at a young age, but shorter overall lifespan, result in a higher lifetime reproductive success and are therefore favoured by natural selection. Essentially, ageing is therefore the result of investing resources in reproduction, rather than maintenance of the body (the "Disposable Soma" theory).
Organismal ageing is generally characterized by the declining ability to respond to stress, increasing homeostatic imbalance and increased risk of disease. Because of this, death is the ultimate consequence of ageing. Not all organisms age, presumably due to different selective pressures during evolution. Organisms that are suspected not to age include certain fish (e.g., Sturgeon), plants, and hydra.
Some researchers are treating ageing as a "disease" in gerontology (specifically biogerontologists). That is, as genes that have an effect on ageing are discovered, ageing is increasingly being regarded in a similar fashion to other genetic conditions; potentially "treatable." As an example of genes known to affect the ageing process, the sirtuin family of genes have been shown to have a significant effect on the lifespan of yeast and nematodes. Numerous other examples exist of genes that affect lifespan including RAS1 and RAS2 (yeast genes, although a human homologue exists). Over-expression of RAS2 increases lifespan in yeast substantially.
In addition to genetic ties to lifespan, diet has been shown to substantially affect lifespan in many animals. Specifically, caloric restriction (that is, restricting calories to 30-50% less than an ''ad libitum'' animal would consume, while still maintaining proper nutrient intake), has been shown to increase lifespan in mice up to 50%. Caloric restriction works on many other species beyond mice (including species as diverse as yeast and Drosophila), and appears (though the data is not conclusive) to increase lifespan in primates according to a study done on Rhesus monkeys at the National Institute of Health (US).
Hans Baldung Grien's ''The Ages And Death'', c. 1540-1543
An elderly Iraqi man
A UK pensioner, 2005

Drug companies are currently searching for ways to mimic the lifespan-extending affects of caloric restriction without having to severely reduce food consumption, and with respect to cellular senescence, it has been shown that individual cells can be immortalized by the introduction of an additional gene for telomerase.

Dividing the lifespan


A human life is often divided into various ages. Because biological changes are slow moving and vary from person to person, arbitrary dates are usually set to mark periods of human life.
In some cultures the divisions given below are quite varied.
In the USA, adulthood legally begins at the age of eighteen or nineteen, while old age is considered to begin at the age of legal retirement (approximately 65).

★ Pre-conception: Ovum, Spermatozoon, Pre-existence

★ Conception: Fertilization

Pre-birth: Conception to birth

Infancy: Birth to 2

Childhood: 2 to 13

Adolescence: 13 to 19

Early Adulthood: 20 to 39

Middle Adulthood: 40 to 59

Late Adulthood: 60+

Death

★ Post-Death: Decomposition, Cryonics, (Afterlife, Ghost)
Ages can also be divided by decade:

★ Denarian: someone between 10 and 19 years of age

★ Vicenarian: someone between 20 and 29 years of age

★ Tricenarian: someone between 30 and 39 years of age

★ Quadragenarian: someone between 40 and 49 years of age

★ Quinquagenarian: someone between 50 and 59 years of age

★ Sexagenarian: someone between 60 and 69 years of age

★ Septuagenarian: someone between 70 and 79 years of age

★ Octogenarian: someone between 80 and 89 years of age

★ Nonagenarian: someone between 90 and 99 years of age

Centenarian: someone between 100 and 109 years of age

Supercentenarian: someone over 110 years of age
See also Seven ages of man for an older system of dividing the human life.

Cultural variations


In some cultures (for example Serbian and Russian) there are two ways to express age: by counting years with or without including current year. For example, it could be said about the same person that he is twenty years old or that he is in twenty-first year of his life.
Considerable numbers of cultures have less of a problem with age compared with what has been described above, and it is seen as an important status to reach stages in life, rather than defined numerical ages. Advanced age is given more respect and status.
Traditional Chinese culture use different ageing method, called ''Xusui'' (虛歲) with respect to common ageing which called ''Zhousui'' (周歲). In the ''Xusui'' method, people are born at age 1, not age 0. See also East Asian age reckoning for more information.

Society


Legal

There are variations in many countries as to what age a person legally becomes an adult.
Most legal systems define a specific age for when an individual is allowed or obliged to do something. These ages include voting age, drinking age, age of consent, age of majority, age of criminal responsibility, marriageable age, age where one can hold public office, and mandatory retirement age. Admission to a movie for instance, may depend on age according to a motion picture rating system. A bus fare might be discounted for the young or old.
Similarly in many countries in jurisprudence, the defence of infancy is a form of defence by which a defendant argues that, at the time a law was broken, they were not liable for their actions, and thus should not be held liable for a crime. Many courts recognize that defendants, which are considered to be juveniles, may avoid criminal prosecution on account of their age.
Economics and marketing

The economics of ageing are also of great import. Children and teenagers have little money of their own, but most of it is available for buying consumer goods. They also have considerable impact on how their parents spend money.
Young adults are an even more valuable cohort. They often have jobs with few responsibilities such as a mortgage or children. They do not yet have set buying habits and are more open to new products.
The young are thus the central target of marketers.[1] Television is programmed to attract the 15 to 35 years olds. Movies are also built around appealing to the young.
Impact of ageing on health care demand

Many societies in the rich world, i.e. Western Europe and Japan, have ageing populations. While the effects on society are complex, there is a concern about the impact on health care demand. Saltman et al. (2006) argue that the large number of suggestions in the literature for specific interventions to cope with the expected increase in demand for long-term care in ageing societies can be organized under four headings: improve system performance; redesign service delivery; support informal caregivers; and shift demographic parameters.

Effects


Cognitive

Steady decline in many cognitive processes are seen across the lifespan, starting in one's thirties. Research has focused in particular on memory and ageing, and has found decline in many types of memory with ageing, but not in semantic memory or general knowledge such as vocabulary definitions, which typically increases or remains steady.

Societal ageing


Societal ageing refers to the demographic ageing of populations and societies as described by Professor Sarah Harper in 2006 in her book "Ageing Societies: Myths, Challenges and Opportunities". Cultural differences in attitudes to ageing have been studied by Best and Williams (see the article on cross-cultural psychology).
Emotional

Given the physical and cognitive declines seen in ageing, a surprising finding is that emotional experience improves with age. Older adults are better at regulating their emotions and experience negative affect less frequently than younger adults and show a positivity effect in their attention and memory. The emotional improvements show up in longitudinal studies as well as in cross-sectional studies, and so cannot be entirely due to only the happier individuals surviving.

Successful ageing


The concept of "successful ageing", as Strawbridge et al. (2002), have pointed out, can be traced back to the 1950s, but was popularised in an article by Rowe and Kahn (1987). These authors believed that former research into ageing had exaggerated the extent to which health disabilities, such as diabetes or osteoporosis, could be attributed exclusively to age, and also criticised former research in gerontology for exaggerating the homogeneity of samples of elderly people.
In a subsequent publication, Rowe and Kahn (1997) criticise earlier work for making what, to them, is an over-simplistic distinction between pathologic and non-pathologic ageing, and distinguish between "normal ageing" (marked by high risk of illness), and "successful ageing" (marked by low risk of disability and high cognitive and physical functioning). They define "successful ageing" more specifically as consisting of three components:
# Low probability of disease or disability;
# High cognitive and physical function capacity;
# Active engagement with life.
Criticisms of Rowe and Kahn's work has been noted by Strawbridge et al. (2002), who note that more liberal definitions of "successful ageing" than those proposed by Rowe and Kahn result in greater percentages of elderly adults reaching successful ageing, and that self-reported successful ageing suggests a greater number of elderly people reach successful ageing than does an operational measure based on Rowe and Kahn's conceptualisations. Indeed, Strawbridge et al. (2002) note that the term "successful ageing", insofar as it implies competitiveness and that "normal ageing" is a failure, is itself problematic, and review alternative terms (such as "healthy ageing") that have been proposed.
Aldwin and Gilmer (2004) have argued in favour of the term "optimal ageing" in favour of "successful ageing. They argue that the latter term is too likely to obscure how many elderly people do suffer some health detriments, and also note the cultural diversity in approaches to death that complicate usage of a term such as "successful ageing", noting how, in Western Europe and Northern America, how people may approach death may differ from approaches taken in other cultures.

Theories of aging


'Modernization Theory'
This is the view that the status of the elderly has declined since industrialization and the spread of technology.
'Disengagement Theory'
This is the idea that separation of older people from active roles in society is normal and appropriate, and benefits both society and older individuals.
'Activity Theory'
A view holding that the more active people are, the more likely they are to be satisfied with life.
'Continuity Theory'
The view that in aging people are inclined to maintain, as much as they can, the same habits, personalities, and styles of life that they have developed in earlier years.
'Cognitive Theory'
A view of aging that emphasizes individual subjective perception, rather than actual objective change itself, as the factor that determines behavior associated with advanced age.
'Demographic Transition Theory'
The idea that population aging can be explained by a decline in both birthrates and death rates following industrialization.
'Exchange Theory'
The idea that interaction in social groups is based on the reciprocal balancing of rewards depending on actions performed
'Political Economy Theory'
A societal perspective on the aging process that explains that the status and resources of the elderly, as well as how people age, are shaped by each person's place in the social structure and the economic and political forces that impact their sociopolitical location.
'The theory of gerotranscendence' http://sv.wikipedia.org/wiki/Gerotranscendens
http://www.soc.uu.se/research/gerontology/gerotrans.html
Biological theories

Aging can be very depressing at times.
;'Wear-and-Tear theory': The idea that changes associated with aging are the result of chance damage that accumulates over time.
;'Somatic Mutation Theory': This is the biological theory that aging results from damage to the genetic integrity of the body’s cells.
;'Error Accumulation Theory': This is the idea that aging results from chance events that gradually damage the genetic code.
;'Accumulative-Waste Theory': The biological theory of aging that points to a buildup of cells of waste products that presumably interferes with metabolism.
;'Autoimmune Theory': This is the idea that aging results from gradual decline in the body’s immune system.
;'Aging-Clock Theory': The idea that aging results from a preprogrammed sequence, as in a clock, built into the operation of the nervous or endocrine system of the body.
;'Cross-Linkage Theory': This is the idea that aging results from accumulation of cross-linked compounds that interfere with normal cell function.
;'Free-Radical Theory': The idea that free radicals (unstable and highly reactive organic molecules) create damage that gives rise to symptoms we recognize as aging.
;'Cellular Theory': This is the view that aging can be explained largely by changes in structure and function taking place in the cells of an organism.

Measure of age


The normal point of time from where to measure the age of a human being is from birth. However, this is not how gynaecologists measure age in prenatal development. Rather, age for people not yet born is normally measured in gestational age, taking the last menstruation of the woman as a point of beginning. Alternatively, fertilization age, beginning from fertilization can be taken.

See also



Adultism

Aging brain

Aging Research Centre

Biodemography

Biological immortality

Life expectancy

List of life extension-related topics

Longevity

Maturity (psychological)

Memory and aging

Orthomolecular medicine

Population ageing

Retirement

Senescence

The Grim Reaper Gene

Youth bulge

Notes


1. Does Age Quash Our Spirit of Adventure?

Further reading



The arrow of time - a photo-essay of a family ageing, with yearly portraits over 30 years

Brain Health Roadmap by CDC and Alzheimer's Association - an article on their joint initiative

References



★ Aldwin, C.M. & Gilmer, D.F. (2004). Health, Illness and Optimal Ageing. London: Sage. ISBN 0-7619-2259-8

★ Bass, S.A. (2006). Gerontological Theory: The Search for the Holy Grail. The Gerontologist, 46, 139-144.

★ Charles, S.T., Reynolds, C.A., & Gatz, M. (2001). Age-related differences and change in positive and negative affect over 23 years. ''Journal of Personality and Social Psychology'', 80, 136-151.

★ Mather, M., & Carstensen, L. L. (2005). Aging and motivated cognition: The positivity effect in attention and memory. ''Trends in Cognitive Sciences'' '9', 496-502. PDF

★ Masoro E.J. & Austad S.N.. (eds.): Handbook of the Biology of Aging, Sixth Edition. Academic Press. San Diego, CA, USA, 2006. ISBN 0-12-088387-2

★ Rowe, J.D. & Kahn, R.L. (1987). Human ageing: Usual and successful. Science, 237, 143-149

★ Rowe, J.D. & Kahn, R.L.(1997). Successful ageing. The Gerontologist, 37 (4) 433-40

★ Strawbridge, W.J., Wallhagen, M.I. & Cohen, R.D. (2002). Successful ageing and well-being: Self-rated compared with Rowe and Kahn. The Gerontologist, 42, (6)

★ Zacks, R.T., Hasher, L., & Li, K.Z.H. (2000). Human memory. In F.I.M. Craik & T.A. Salthouse (Eds.), ''The Handbook of Aging and Cognition'' (pp. 293-357). Mahwah, NJ: Erlbaum.

★ Saltman, R.B., Dubois, H.F.W. and Chawla, M. (2006) The impact of aging on long-term care in Europe and some potential policy responses, International Journal of Health Services, 36(4): 719-746.

Thesaurus of Aging Terminology (5,1MB, 272p), 8th edition (2005), AARP
Moody, Harry R. Aging: Concepts and Controversies. 5th ed. California: Pine Forge Press, 2006.

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