'Americus' may mean:
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Americus, Georgia, a city with a population of around 17,000
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Americus, Indiana, a small town in Washington Township
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Americus, Kansas, a city with a population of around 900
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Imre of Hungary (died 1031), also known as ''Saint Americus'' or ''Emeric'', a Hungarian prince
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Amerigo Vespucci (1454-1512) Italian merchant, explorer and cartographer whose first name was ''Americus'' in Latin