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:''This article is about the ancient cities named Apamea; for the moth genus, see Apamea (moth genus)''
'Apamea' or 'Apameia' (Greek: Απάμεια) is the name of several Hellenistic cities in western Asia, after Apama, the wife of Seleucus I Nicator:

★ Apamea (Syria), on the Orontes River, northwest of Hama, Syria

★ Apamea (Babylonia), on the Tigris near the Euphrates, precise location unknown, now in Iraq

★ Apamea (Sittacene), on the Tigris, precise location unknown, now in Iraq

★ Apamea (Media), in Media, near Laodicea (Nahavand, Iran), precise location unknown

★ Apamea Myrlea, formerly ''Myrlea'' and ''Brylleion'', in Bithynia, on the Sea of Marmara; currently near Mudanya, Bursa Province, Turkey

★ Apamea (Euphrates), in Osroene, opposite Zeugma on the Euphrates, now flooded by the Birecik Dam, Turkey

★ Apamea (Phrygia), formerly ''Kibotos'', commercial center of Phrygia, near Celaenae, now at Dinar, Afyonkarahisar Province, Turkey

★ Apamea Ragiana, south of the Caspian Gates in Parthia (later Media); now in Iran