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EspañolBONE MORPHOGENETIC PROTEIN 2
(Redirected from BMP2)
'Bone morphogenetic protein 2' or 'BMP-2' is a protein that belongs to the TGF-β superfamily of proteins. It, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. It is involved in the Hedgehog pathway, TGF-beta signaling pathway, and the Cytokine-cytokine receptor interaction. It is involved also in cardiac cell differentiation and epithelial to mesenchymal transition.
BMP-2 and BMP-7 are osteogenic BMPs: they have been demonstrated to potently induce osteoblast differentiation in a variety of cell types.
Bone morphogenetic protein 2 has been shown to stimulate the production of bone and recombinant human protein (rhBMP-2) is currently available in for orthopaedic usage in the United States. Implantation of BMP-2 in a collagen sponge induces new bone formation and can be used for the treatment of bony defects, delayed union, and non-union.
For More Information visit: www.infusebonegraft.com
★ Online Mendelian Inheritance in Man record:
'Bone morphogenetic protein 2' or 'BMP-2' is a protein that belongs to the TGF-β superfamily of proteins. It, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. It is involved in the Hedgehog pathway, TGF-beta signaling pathway, and the Cytokine-cytokine receptor interaction. It is involved also in cardiac cell differentiation and epithelial to mesenchymal transition.
BMP-2 and BMP-7 are osteogenic BMPs: they have been demonstrated to potently induce osteoblast differentiation in a variety of cell types.
| Contents |
| Medical Uses |
| External links |
Medical Uses
Bone morphogenetic protein 2 has been shown to stimulate the production of bone and recombinant human protein (rhBMP-2) is currently available in for orthopaedic usage in the United States. Implantation of BMP-2 in a collagen sponge induces new bone formation and can be used for the treatment of bony defects, delayed union, and non-union.
For More Information visit: www.infusebonegraft.com
External links
★ Online Mendelian Inheritance in Man record:
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