العربية
中国
Français
Deutsch
Ελληνική
हिन्दी
Italiano
日本語
Português
Русский
EspañolBIOSTATISTICS
:''For the automated recognition of people based on intrinsic physical or behavioural traits, see Biometrics.''
'Biostatistics' or 'biometry' is the application of statistics to a wide range of topics in biology. It has particular applications to medicine and to agriculture.
''Note on terminology'': Although the terms "biostatistics" and "biometry" are sometimes used interchangeably, "biometry" is more often used of biological or agricultural applications and "biostatistics" of medical applications. In older sources "biometrics" is used as a synonym for "biometry", but this term has now been largely usurped by the information technology industry.
Biostatistical reasoning and modeling were critical information of the foundation theories of modern biology. In the early 1900s, after the rediscovery of Mendel's work, the conceptual gaps in understanding between genetics and evolutionary Darwinism led to vigorous debate between biometricians such as Walter Weldon and Karl Pearson and Mendelians such as Charles Davenport and William Bateson. By the 1930s statisticians and models built on statistical reasoning had helped to resolve these differences and to produce the Neo-Darwinian Modern evolutionary synthesis.
The leading figures in the establishment of this synthesis all relied on statistics and developed its use in biology.
★ Sir Ronald A. Fisher developed several basic statistical methods in support of his work ''The Genetical Theory of Natural Selection''
★ Sewall G. Wright used statistics in the development of modern population genetics
★ J. B. S Haldane's book, ''The Causes of Evolution'', reestablished natural selection as the premier mechanism of evolution by explaining it in terms of the mathematical consequences of Mendelian genetics.
These individuals and the work of other biostatisticians, mathematical biologists, and statistically inclined geneticists helped bring together evolutionary biology and genetics into a consistent, coherent whole that could begin to be quantitatively modeled.
In parallel to this overall development, the pioneering work of D'Arcy Thompson in ''On Growth and Form'' also helped to add quantitative discipline to biological study.
Despite the fundamental importance and frequent necessity of statistical reasoning, there is nonetheless a tendency of biologists to distrust or deprecate results which are not qualitatively apparent. One anecdote describes Thomas Hunt Morgan banning the Frieden calculator from his department at Caltech, saying "Well, I am like a guy who is prospecting for gold along the banks of the Sacramento River in 1849. With a little intelligence, I can reach down and pick up big nuggets of gold. And as long as I can do that, I'm not going to let any people in my department waste scarce resources in placer mining."[1] Educators are now adjusting their curricula to focus on more quantitative concepts and tools.[2]
Almost all educational programmes in biostatistics are at postgraduate level. They are most often found in schools of public health, affiliated with schools of medicine, forestry, or agriculture or as a focus of application in departments of statistics. In the United States, several universities have dedicated biostatistics departments; many other top-tier universities integrate Biostatistics faculty into Statistics (or other) departments.
Many universities that deal with ecological research have a biostatistics course that introduces concepts such as hypothesis testing for univariate and sometimes multivariate data sets with one, two, or more samples. Often this is combined or followed with some kind of experimental design course.
★ Public health, including epidemiology, health services research, nutrition, and environmental health,
★ Design and analysis of clinical trials in medicine
★ Genomics, population genetics, and statistical genetics in populations in order to link variation in genotype with a variation in phenotype. This has been used in agriculture to improve crops and farm animals. In biomedical research, this work can assist in finding candidates for gene alleles that can cause or influence predisposition to disease in human genetics
★ Ecology
★ Biological sequence analysis
Statistical methods are beginning to be integrated into medical informatics, public health informatics, and bioinformatics
Biostatistics draws quantitative methods from fields such as:
★ statistics,
★ operations research,
★ computer science,
★ economics, and, generally,
★ mathematics
★ Bioinformatics
★ Mathematical biology
★ Important publications in biostatistics
★ The International Biometric Society
★ BIOREL resource for quantitative estimation of the gene network bias in relation to available database information
★ The American Statistical Association
★ The Royal Statistical Society
★ The Collection of Biostatistics Research Archive
★ The American Association of Schools of Public Health
★ The Biostatistics Collaboration of Australia
★ Statistical Applications in Genetics and Molecular Biology
★ Statistics in Medicine
★ The International Journal of Biostatistics
★ Journal of Biopharmaceutical Statistics
★ Biostatistics
★ Biometrics
★ Biometrika
★ Biometrical Journal
1. Academic Economics: Strengths and Faults After Considering Interdisciplinary Needs Charles T. Munger
2. Spotlight:application of quantitative concepts and techniques in undergraduate biology
'Biostatistics' or 'biometry' is the application of statistics to a wide range of topics in biology. It has particular applications to medicine and to agriculture.
''Note on terminology'': Although the terms "biostatistics" and "biometry" are sometimes used interchangeably, "biometry" is more often used of biological or agricultural applications and "biostatistics" of medical applications. In older sources "biometrics" is used as a synonym for "biometry", but this term has now been largely usurped by the information technology industry.
| Contents |
| Biostatistics and the history of biological thought |
| Education and Training Programs |
| Applications of biostatistics |
| Related Fields |
| See also |
| External links |
| Journals |
| References |
Biostatistics and the history of biological thought
Biostatistical reasoning and modeling were critical information of the foundation theories of modern biology. In the early 1900s, after the rediscovery of Mendel's work, the conceptual gaps in understanding between genetics and evolutionary Darwinism led to vigorous debate between biometricians such as Walter Weldon and Karl Pearson and Mendelians such as Charles Davenport and William Bateson. By the 1930s statisticians and models built on statistical reasoning had helped to resolve these differences and to produce the Neo-Darwinian Modern evolutionary synthesis.
The leading figures in the establishment of this synthesis all relied on statistics and developed its use in biology.
★ Sir Ronald A. Fisher developed several basic statistical methods in support of his work ''The Genetical Theory of Natural Selection''
★ Sewall G. Wright used statistics in the development of modern population genetics
★ J. B. S Haldane's book, ''The Causes of Evolution'', reestablished natural selection as the premier mechanism of evolution by explaining it in terms of the mathematical consequences of Mendelian genetics.
These individuals and the work of other biostatisticians, mathematical biologists, and statistically inclined geneticists helped bring together evolutionary biology and genetics into a consistent, coherent whole that could begin to be quantitatively modeled.
In parallel to this overall development, the pioneering work of D'Arcy Thompson in ''On Growth and Form'' also helped to add quantitative discipline to biological study.
Despite the fundamental importance and frequent necessity of statistical reasoning, there is nonetheless a tendency of biologists to distrust or deprecate results which are not qualitatively apparent. One anecdote describes Thomas Hunt Morgan banning the Frieden calculator from his department at Caltech, saying "Well, I am like a guy who is prospecting for gold along the banks of the Sacramento River in 1849. With a little intelligence, I can reach down and pick up big nuggets of gold. And as long as I can do that, I'm not going to let any people in my department waste scarce resources in placer mining."[1] Educators are now adjusting their curricula to focus on more quantitative concepts and tools.[2]
Education and Training Programs
Almost all educational programmes in biostatistics are at postgraduate level. They are most often found in schools of public health, affiliated with schools of medicine, forestry, or agriculture or as a focus of application in departments of statistics. In the United States, several universities have dedicated biostatistics departments; many other top-tier universities integrate Biostatistics faculty into Statistics (or other) departments.
Many universities that deal with ecological research have a biostatistics course that introduces concepts such as hypothesis testing for univariate and sometimes multivariate data sets with one, two, or more samples. Often this is combined or followed with some kind of experimental design course.
Applications of biostatistics
★ Public health, including epidemiology, health services research, nutrition, and environmental health,
★ Design and analysis of clinical trials in medicine
★ Genomics, population genetics, and statistical genetics in populations in order to link variation in genotype with a variation in phenotype. This has been used in agriculture to improve crops and farm animals. In biomedical research, this work can assist in finding candidates for gene alleles that can cause or influence predisposition to disease in human genetics
★ Ecology
★ Biological sequence analysis
Statistical methods are beginning to be integrated into medical informatics, public health informatics, and bioinformatics
Related Fields
Biostatistics draws quantitative methods from fields such as:
★ statistics,
★ operations research,
★ computer science,
★ economics, and, generally,
★ mathematics
See also
★ Bioinformatics
★ Mathematical biology
★ Important publications in biostatistics
External links
★ The International Biometric Society
★ BIOREL resource for quantitative estimation of the gene network bias in relation to available database information
★ The American Statistical Association
★ The Royal Statistical Society
★ The Collection of Biostatistics Research Archive
★ The American Association of Schools of Public Health
★ The Biostatistics Collaboration of Australia
Journals
★ Statistical Applications in Genetics and Molecular Biology
★ Statistics in Medicine
★ The International Journal of Biostatistics
★ Journal of Biopharmaceutical Statistics
★ Biostatistics
★ Biometrics
★ Biometrika
★ Biometrical Journal
References
1. Academic Economics: Strengths and Faults After Considering Interdisciplinary Needs Charles T. Munger
2. Spotlight:application of quantitative concepts and techniques in undergraduate biology
This article provided by Wikipedia. To edit the contents of this article, click here for original source.
psst.. try this: add to faves
