CEFRADINE

{{drugbox |
| IUPAC_name = (6''R'',7''R'')-7-{[(2''R'')-2-amino-2-(1-cyclohexa-1,4-
dienyl)acetyl]amino}-3-methyl-8-oxo-5-thia-
1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
| image = Cefradine.svg
| CAS_number = 38821-53-3
| ATC_prefix = J01
| ATC_suffix = DB09
| PubChem = 38103
| DrugBank =
| C = 16 | H = 19 | N = 3 | O = 4 | S = 1
| molecular_weight = 349.406 g/mol
| bioavailability = Well absorbed
| protein_bound = <10%
| metabolism = Nil
| elimination_half-life = 0.9 hours
| excretion = Renal, unchanged
| pregnancy_AU =
| pregnancy_US =
| pregnancy_category =
| legal_status = Rx-only
| routes_of_administration = Oral, IM, IV
}}
'Cefradine' (INN) or 'cephradine' (former BAN) is a first generation cephalosporin antibiotic.

Contents

Indications

Dosage

Formulations

References

Indications

It has similar spectrum of activity to cefalexin.

Dosage

Dosage by mouth for adults is 250–500 mg every 6 hours, or 500 mg to 1 g every 12 hours. In severe infections up to 1 g every 6 hours may be used. Dosages for children are based upon their weight with 25–50 mg/kg total daily dose given in 2–4 divided doses.

Formulations

Caspules containing 250 mg or 500 mg, Syrup containing 250 mg/5 ml, or vials for injection containing 500 mg or 1 g.

References

★ British National Formulary ''45'' March 2003