CHINESE HAMSTER OVARY CELL

'Chinese Hamster Ovary cells' ('CHO' cells) are a cell line derived from Chinese Hamster ovary cells. They are often used in biological and medical research. They were introduced in the 1960s and are used in a cultured monolayer in culture flasks. They require the amino acid proline in their culture medium; this property makes them ideal for genetics research.
CHO cells are used in studies of genetics, toxicity screening, nutrition and gene expression particularly expression of recombinant proteins.

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See also

Reference

External links

See also

★ Cell culture

★ Drug development

★ Pre-clinical development

★ Caco-2

Reference

Tjio J. H., Puck T. T., Genetics of somatic mammalian cells. II. chromosomal constitution of cells intissue culture. J. Exp. Med. 1958; 108: 259-271.

External links

★ Maintaining Chinese Hamster Ovary Cell Cultures - How to Passage CHO Cells

★ Phase contrast images of CHO cells

★ Article from 1958 on culturing euploid cells

★ http://www.biotech.ist.unige.it/cldb/cl721.html