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(Redirected from Cytotoxic)
'Cytotoxicity' is the quality of being toxic to cells. Examples of toxic agents are a chemical substance or an immune cell.
Cytotoxicity can be measured by the MTT assay, Trypan blue (TB) assay, Sulforhodamine B (SRB) assay, WST assay and clonogenic assay.
''Antibody-dependent cell-mediated cytotoxicity'' (''ADCC'') describes the cell-killing ability of certain lymphocytes, which requires the target cell being marked by an antibody. ''Lymphocyte-mediated cytotoxicity'', on the other hand, does not have to be mediated by antibodies; nor does ''complement-dependent cytotoxicity'' (''CDC''), which is mediated by the complement system.
Three groups of cytotoxic lymphocytes are distinguished:

★ Cytotoxic T cells

★ Natural killer cells

★ Natural Killer T cells

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