ENZYME ACTIVATOR

'Enzyme activators' are molecules that bind to enzymes and increase their activity. These molecules are often involved in the allosteric regulation of enzymes in the control of metabolism. An example of an enzyme activator working in this way is fructose 2,6-bisphosphate, which activates phosphofructokinase 1 and increases the rate of glycolysis in response to the hormone glucagon.^[1][2]

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References

References

1. Covalent control of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: insights into autoregulation of a bifunctional enzyme, Kurland IJ, Pilkis SJ, , , Protein Sci., 1995
2. Fructose-2,6-bisphosphate and control of carbohydrate metabolism in eukaryotes, Okar DA, Lange AJ, , , Biofactors, 1999