FLAVIVIRIDAE
The '''Flaviviridae''' are a family of viruses that are primarily spread through arthropod vectors (mainly ticks and mosquitoes). They include the following genera:
★ Genus ''Flavivirus'' (type species ''Yellow fever virus'', others include ''West Nile virus'' and ''Dengue Fever'')—contains 67 identified human and animal viruses
★ Genus ''Hepacivirus'' (type species ''Hepatitis C virus'', the single member)
★ Genus ''Pestivirus'' (type species ''Bovine virus diarrhea'', others include classical swine fever or hog cholera)—contains viruses infecting non-human mammals
''Flaviviridae'' have monopartite, linear, single-stranded RNA genomes of positive polarity, 9.6- to 12.3-kilobase in length. The 5'-termini of flaviviruses carry a methylated nucleotide cap, while other members of this family are uncapped and encode an internal ribosome entry site. Virus particles are enveloped and spherical, about 40-60 nm in diameter.
Major diseases caused by the ''Flaviviridae'' family include:
★ Dengue fever
★ Japanese encephalitis
★ Kyasanur Forest disease
★ Murray Valley encephalitis
★ St. Louis encephalitis
★ Tick-borne encephalitis
★ West Nile encephalitis
★ Yellow fever
★ Hepatitis C Virus Infection
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