FLAVIVIRIDAE


The '''Flaviviridae''' are a family of viruses that are primarily spread through arthropod vectors (mainly ticks and mosquitoes). They include the following genera:

★ Genus ''Flavivirus'' (type species ''Yellow fever virus'', others include ''West Nile virus'' and ''Dengue Fever'')—contains 67 identified human and animal viruses

★ Genus ''Hepacivirus'' (type species ''Hepatitis C virus'', the single member)

★ Genus ''Pestivirus'' (type species ''Bovine virus diarrhea'', others include classical swine fever or hog cholera)—contains viruses infecting non-human mammals
''Flaviviridae'' have monopartite, linear, single-stranded RNA genomes of positive polarity, 9.6- to 12.3-kilobase in length. The 5'-termini of flaviviruses carry a methylated nucleotide cap, while other members of this family are uncapped and encode an internal ribosome entry site. Virus particles are enveloped and spherical, about 40-60 nm in diameter.
Major diseases caused by the ''Flaviviridae'' family include:

Dengue fever

Japanese encephalitis

Kyasanur Forest disease

Murray Valley encephalitis

St. Louis encephalitis

Tick-borne encephalitis

West Nile encephalitis

Yellow fever

Hepatitis C Virus Infection

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