GEORGE CHURCH
'George Church' (1954- ) is an American molecular geneticist. He is currently Professor of Genetics [1] at Harvard Medical School and Professor of Health Sciences & Technology [2] at Harvard and MIT. With Walter Gilbert he developed the first direct genomic sequencing method in 1984[3] and helped initiate the Human Genome Project in 1984 [4] while he was a Research Scientist at newly-formed Biogen Inc. He invented the broadly-applied concepts of molecular multiplexing and tags[5], homologous recombination methods [6], and DNA array synthesizers. Technology transfer of automated sequencing & software to Genome Therapeutics Corp. resulted in the first commercial genome sequence, (the human pathogen, ''Helicobacter pylori'') in 1994 [7]. He initiated the Personal Genome Project (PGP) [8] in 2005 and research on synthetic biology. He is director of the U.S. Department of Energy Center on Bioenergy at Harvard & MIT [9] and director of the National Institutes of Health (NHGRI) Center of Excellence in Genomic Science at Harvard, MIT & Washington University [10]. He has been advisor to 22 companies, most recently co-founding (with Joseph Jacobson, Jay Keasling, and Drew Endy) Codon Devices, a biotech startup dedicated to synthetic biology[11] and (with Chris Somerville) founding LS9, which is focused on biofuels [12]. He is a senior editor for Nature EMBO Molecular Systems Biology.
★ Church Lab webpage
★ New Polony DNA Sequencing Methods
★ Biosketch on Edge.org
1. HMS Genetics Faculty
2. HST
3. Genomic Sequencing, Church GM, Gilbert W, , , Proc Nat Acad Sci USA, 1984
4. The Alta summit, December 1984, Cook-Deegan RM, , , Genomics, 1989
5. Multiplex Sequencing, Church GM, Kieffer-Higgins S., , , Science, 1984
6. Methods for generating precise deletions and insertions in the genome of wild-type ''Escherichia coli'': application to open reading frame characterization, Link AJ, Phillips D, Church GM, , , J Bacteriol., 1997
7. Capitalizing on the genome, , , , Nature Genetics, 1996 [1]
8. The personal genome project, Church GM, , , Mol Syst Biol., 2005
9. DOE Genomes to Life Center
10. Centers of Excellence in Genomic Science Awards
11. Photoshop For DNA, Herper M, , , Forbes, 2006 [2]
12. San Francisco Business Times - March 12, 2007
| Contents |
| External links |
| References |
External links
★ Church Lab webpage
★ New Polony DNA Sequencing Methods
★ Biosketch on Edge.org
References
1. HMS Genetics Faculty
2. HST
3. Genomic Sequencing, Church GM, Gilbert W, , , Proc Nat Acad Sci USA, 1984
4. The Alta summit, December 1984, Cook-Deegan RM, , , Genomics, 1989
5. Multiplex Sequencing, Church GM, Kieffer-Higgins S., , , Science, 1984
6. Methods for generating precise deletions and insertions in the genome of wild-type ''Escherichia coli'': application to open reading frame characterization, Link AJ, Phillips D, Church GM, , , J Bacteriol., 1997
7. Capitalizing on the genome, , , , Nature Genetics, 1996 [1]
8. The personal genome project, Church GM, , , Mol Syst Biol., 2005
9. DOE Genomes to Life Center
10. Centers of Excellence in Genomic Science Awards
11. Photoshop For DNA, Herper M, , , Forbes, 2006 [2]
12. San Francisco Business Times - March 12, 2007
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