GLOMERULAR BASEMENT MEMBRANE

The 'glomerular basement membrane' is the basal laminal portion of the glomerulus which performs the actual filtration though the filtration slits between the podocytes , separating the blood on the inside from the filtrate on the outside.^[1]

Contents

Layers

Pathology

See also

References

External links

Layers

The GBM contains three layers: ^[2]

lamina rara externa	by heparan sulfate	blocks by charge
lamina densa	by type 4 collagen	blocks by size
lamina rara interna	heparan sulfate	blocks by charge

Pathology

★ Goodpasture's syndrome is also known as "anti-glomerular basement membrane disease".

See also

★ basement membrane

★ nephrin

References

1. - "Basement Membrane"
2. http://www.jci.org/cgi/content/full/116/8/2090/F1

External links

★

★ "The GBM and its disorders" at dmed.ed.ac.uk

★ Histology at harvard.edu

★ Structure at wramc.army.mi