HSP90 CIS-REGULATORY ELEMENT

The 'Hsp90 cis regulatory element' is an RNA element found in the 5' UTR of the Drosophila hsp90 mRNA that is required for increased translational efficiency during the heat shock response. The hsp90 gene product is involved in the Drosophila heat shock response and translation of the hsp90 mRNA is very inefficient under normal growth temperatures. When heat shock occurs translation becomes more efficient.^[1]

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1. Translational regulation of Hsp90 mRNA. AUG-proximal 5'-untranslated region elements essential for preferential heat shock translation, , R, Ahmed, J Biol Chem, 2004

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