
hypericin structure
'Hypericin' is a red-coloured
anthraquinone-derivative, which is one of the principal active constituents of
Hypericum (
Saint John's wort). Hypericin is believed to act as an
antibiotic and non-specific
kinase inhibitor. Hypericin may inhibit reuptake of
dopamine β-hydroxylase, leading to increased
dopamine levels, although thus possibly decreasing
norepinephrine and
epinephrine.
The large
chromophore system in the molecule means that it can cause
photosensitivity when ingested beyond threshold amounts. Because hypericin accumulates preferentially on
cancerous tissues, it is also used as an indicator of cancerous cells. In addition, hypericin is under research as an agent in
photodynamic therapy, whereby a biochemical is absorbed by an organism to be later activated with spectrum-specific light from specialized lamps or
laser sources, for therapeutic purposes.
External links
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Hypericin: the active ingredient in Saint John’s Wort