ISABEL OF COIMBRA

'Isabel of Coimbra' (Isabella of Portugal) (1 March 1432–December 2 1455) was a princess of Portugal and the first wife of King Afonso V of Portugal.
She was a daughter of Infante Pedro, Duke of Coimbra and Isabel of Aragon. Her maternal grandfather was Jaume II, Count of Urgell.
Isabel and Afonso V were married on May 6, 1448. Both the bride and groom were sixteen. They had three children:

★ 'Prince John' (January 29, 1451-April 22 1455)

★ 'Princess Joan' (February 6, 1452-May 12, 1490): Known as Saint Joan of Portugal or Saint Joan Princess. Canonized in 1693 by Pope Innocent XII.

★ 'John II of Portugal' (March 3, 1455-October 25, 1495): Succeeded his father as 13th King of Portugal.
Isabel died unexpectly eight months after the birth of her last child, aged twenty-three, possibly by poisoning.