METHYLMALONYL-COA

(Redirected from Methylmalonyl-coenzyme A)

'Methylmalonyl-CoA' is the coenzyme A linked form of methylmalonic acid.
It is formed from Propionyl-CoA by Propionyl-CoA carboxylase.
It is converted into Succinyl-CoA by Methylmalonyl-CoA mutase, in a reaction that requires Vitamin B12 as a cofactor. In this way, it enters the Krebs cycle, and is thus part of one of the anaplerotic reactions.

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