NORMAL ANION GAP ACIDOSIS

In renal physiology, 'normal anion gap acidosis', and less precisely 'non-anion gap acidosis', is an acidosis that is ''not'' accompanied by an anion gap.

Contents

Differential diagnosis

Causes

References

Differential diagnosis

The differential diagnosis of normal anion gap acidosis is relatively short (when compared to the differential diagnosis of ''acidosis''):

★ Hyperalimentation

★ Acetazolamide and other carbonic anhydrase inhibitors

★ Renal tubular acidosis

★ Diarrhea

★ Ureteroenteric fistula - an abnormal connection (fistula) between a ureter and the gastrointestinal tract

★ Pancreaticoduodenal fistula - an abnormal connection between the pancreas and duodenum
It can be remembered with the mnemonic ''HARD-UP''.^[1]

Causes

The most common cause of normal anion gap acidosis is diarrhea.

References

1.