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'Piperonyl butoxide'
Piperonyl butoxide
Systematic name	Piperonyl butoxide
Chemical formula	C19H30N5
Molecular mass	338.43 g/mol
Density	1.05 g/cm3
Melting point	xx.x °C
Boiling point	155 °C
Flash point	171 °C
CAS number	[51-03-6]
SMILES	xxxxx

'Piperonyl butoxide' ('PBO') is a pesticide synergist. It does not, by itself have pesticidal properties. However, when added to insecticide mixtures, typically pyrethrin, pyrethroid, and carbamate insecticides, their potency is increased considerably.
Piperonyl butoxide is a potent cytochrome P450 inhibitor. This family of enzymes act as the principal detoxification pathway for many pesticides. Inhibiting the detoxification pathway allows higher unmetabolised systemic concentrations of the active insecticide to remain within the target animal for a longer period.
Piperonyl butoxide is moderately stable, and is a semisynthetic derivative of safrole.
It is debatable whether the substance is oncogenic, mutagenic, or teratogenic in humans. Its acute oral and dermal toxicity in mammals is low, however it is toxic to fish and potentiates rotenone.

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External links

External links

★ National Pesticide Information Center - Piperonyl Butoxide General Fact Sheet