POLYGLYCYLATION

This is a form of post translational modification of glutamate residues of the carboxyl-terminal region tubulin in certain microtubules (eg axonemal) originally discovered in paramecium^[1], and later shown in mammalian neurons as well^[2].

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References

References

1. Redeker, V., Levilliers, N., Schmitter, J.M., Le Caer, J.P., Rossier, J., Adoutte, A., and Bré, M.H. (1994). Polyglycylation of tubulin: a posttranslational modification in axonemal microtubules. Science 266, 1688-1691
( http://www.sciencemag.org/cgi/content/abstract/266/5191/1688 )
2. Asok Banerjee
Coordination of Posttranslational Modifications of Bovine Brain alpha -Tubulin. POLYGLYCYLATION OF Delta 2 TUBULIN
J. Biol. Chem. 277: 46140-46144
( http://www.jbc.org/cgi/content/full/277/48/46140 )