TRANS-ACTIVATION RESPONSE ELEMENT (TAR)

The HIV 'trans-activation response (TAR) element' is an RNA element which is known to be required for the trans-activation of the viral promoter and for virus replication. The TAR hairpin acts as a binding site for the Tat protein and this interaction stimulates the activity of the long terminal repeat promoter.^[1]

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Reference

1. The apical loop of the HIV-1 TAR RNA hairpin is stabilized by a cross-loop base pair, , T, Kulinski, J Biol Chem, 2003

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