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The 'Urserental' (also 'Urseren') is valley of the upper Reuss River in Uri, Switzerland, running southwest to northeast, from Realp to Hospental and Andermatt.
Separated from the main valley of Uri, it connects to the Valais via the Furkapass, to the Grisons via the Oberalppass and to the Ticino via the Gotthard Pass.

The valley was in possession of the Disentis monastery from AD 800. It was colonized by Walser settlers prior to the 12th century.