XY SEX-DETERMINATION SYSTEM

The 'XY sex-determination system' is the sex-determination system found in humans, most other mammals, some insects (''Drosophila'') and some plants (''Ginkgo''). In the XY sex-determination system, females have two of the same kind of sex chromosome (XX), and are called the homogametic sex. Males have two distinct sex chromosomes (XY), and are called the heterogametic sex.
The XY sex determination system was first described independently by Nettie Stevens and Edmund Beecher Wilson in 1905.

Contents
Mechanisms
See also
References
External links

Mechanisms


Some species (including most mammals) have a gene or genes on the Y chromosome that determine maleness. In the case of humans, a single gene (''SRY'') on the Y chromosome acts as a signal to set the developmental pathway towards maleness. Other mammals use several genes on the Y chromosome for that same purpose. Not all male-specific genes are located on the Y chromosome.
Other species (including most ''Drosophila'' species) use the presence of two X chromosomes to determine femaleness. One X chromosome gives putative maleness. The presence of Y chromosome genes are required for normal male development.
Humans, as well as some other organisms, can have a chromosomal arrangement that is contrary to their phenotypic sex, that is, XX males or XY females. See, for example, XX male syndrome and Androgen insensitivity syndrome.

See also



X chromosome

Y chromosome, for more information about origins of the XY sex-determination system

chromosome, for information on abnormalities of the XY sex-determination system

intersexuality for information on variations in human sexual forms

X-inactivation

sexual differentiation, (human)

testis-determining factor

Barr body

Y-chromosomal Adam

Sex-determination system


X0 sex-determination system


ZW sex-determination system


Haplo-diploid sex-determination system

References


21016

External links



Sex Determination and Differentiation

SRY: Sex determination from the National Center for Biotechnology Information

Sex Chromosomes: What Are They For?

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