 | Brain tumor vaccine CDX-110 University Hospitals Case Medical Center has opened a new brain tumor vaccine trial and candidates are needed. Researchers in the Neurological Institute and Ireland Cancer Center at University Hospitals Case Medical Center are in late-stage trials for an experimental vaccine for the treatment of glioblastoma (GBM), the most aggressive form of brain cancer. So far, the vaccine has been used to treat about 70 patients nationally with virtually no side-effects. Currently 14 patients have enrolled at UH, the only site in Ohio to have opened the study and one of 20 national sites. According to UH neurosurgeon Andrew Sloan, M.D., early results, although not published, seem encouraging. Half of the patients receiving the vaccine have survived for more than 30 months after treatment. The vaccine is designed to teach the body's immune system to attack the tumor without attacking the normal brain cells. Another advantage of the vaccine compared to other experimental treatments is that there are few side-effects to vaccines. For more information or to enroll in the study call 216 844 6054. Source: Cleveland Health News, http://www.wkyc.com (accessed on Feb, 12, 2008) |
 | UCLA Brain Cancer Vaccine DCVAX A vaccine that may save some people from brain cancer. The work is being done at UCLA. One of the subjects, a local musician, is alive three years after treatment. For Kevin Carlberg, 2002 was the "best of times and the worst of times." But life goes on, literally. After surgery, radiation and chemotherapy, Kevin entered a study to see if an experimental vaccine could keep the cancer from coming back. "I mean, so far, so good. It's been, come November 18th, three years since, since surgery and no regrowth," said Carlberg. More info on DC-Vax Brain at http://www.glioblastoma.it |
 | Brain Cancer Vaccine - PART II The vaccine is designed to boost the immune system's response against brain cancer by exposing the antigens, or specific proteins, that brain tumors produce. Each tumor produces several antigens that may be recognized by the immune system. Although the immune system can identify and attack bacteria, viruses and tumors, it does not recognize all brain tumor antigens. When the immune system does not detect these antigens, it can mistake the insidious cancer cells for normal cells and ignore the cancer cells instead of attacking them. But when the immune system has a way to recognize the antigens, the cancer cells are vulnerable to immune attack. To make the vaccine, researchers used an antigen known to be recognized by the immune system. The antigen was partnered with a common form of bacteria, called Listeria monocytogenes. http://cancerres.aacrjournals.org/cgi/content/full/62/8/2287 Taken from KNBC-TV "OnTheVerge" Sept, 18 2007 |
 | Jim Taubert - Brain Cancer Vaccine Saved His Life Cancer vaccines are being studied as treatment for a number of cancers, including brain tumors. They're called vaccines because they stimulate the body's own immune system to fight off tumor cells. A father of two from Sterling is taking part in a clinical trial testing a new brain cancer vaccine. He calls it a miracle and says it's helped him beat the odds. Jim Taubert was just 41-years old when he was diagnosed with a malignant brain tumor in 2006. "All of the sudden I felt like someone had come up from behind and hit me in the head with an ax. It was like I was holding my head together." Doctors told the father of two he had only 6 to 11-months to live. "They told me a giloblastoma was the worst one you can have, it's like an octopus, it wraps around the brain." Jim had surgery to remove as much of the tumor as possible, then had chemo and radiation. He read about an experimental new vaccine they were testing at Duke University Medical Center, so he enrolled in the study. For the past 16 months, Jim has been traveling from Massachusetts to North Carolina once a month to get the vaccine He says his latest MRI shows his tumor is now in remission and he has survived twice as long as expected. "It's gone... Its highly likely this is the vaccine, I just thank god we found it." Jim hopes that Kennedy will beat the odds like he has and that he is grateful for every day he's alive. "You get a second chance... I'm living on borrowed time, but it's worth it." Jim hopes that if and when Sen. Kennedy recovers from his treatment, that he will help lobby for FDA approval for the new vaccine. |
 | Brain Cancer victim given 4 months to live healed Man given 4 months to live because of incurable brain cancer testifies of instant healing |
 | Cell phones and Brain Cancer http://www.electropollution.org/ News release about cell phones and brain cancer. |
 | New Experimental Brain Tumor Treatment - Oncophage November 2006 - A vaccine for treating a recurrent cancer of the central nervous system that occurs primarily in the brain, known as glioma, has shown promising results in preliminary data from a clinical trial at UCSF Medical Center. Findings from the first group of six patients in the study, being conducted at the UCSF Brain Tumor Research Center, showed that vitespen (trademarked as Oncophage), a vaccine made from the patient's own tumor, was associated with tumor-specific immune response in patients with recurrent, high-grade glioma. More info at http://www.glioblastoma.it |
 | Brain Cancer Zapper Using electrical energy to zap cancer cells may sound like a strange idea. But clinical trials at twelve major hospitals around the country are now testing it against the deadliest form of brain cancer. Neuro-oncologist Herb Engelhard explains it's based on a new finding that cells are most vulnerable to electromagnetic fields when they're dividing. In the pilot study in Europe, researchers led by Yoram Palti of the Technion-Israel Institute of Technology tested their prototype device in ten patients with recurrent GBM. Palti, who invented the device, has formed a company called NovoCure that's funding the research. The Phase III trial, which is still recruiting patients, is a randomized controlled study. More info at http://www.glioblastoma.it |
 | Drug Combo Might Offer Hope for Some Brain Tumor Patients Dr. James Vredenburgh, Duke neuro-oncologist and lead investigator, offers a few comments on a new Duke study that shows a combination of bevacizumab -- commonly known as Avastin -- and a standard chemotherapy agent, may increase the amount of time GBM patients can survive without tumor growth, and may significantly increase their overall survival. In part, the combination of drugs chokes off a tumor's blood supply. |
 | Clinical Trial 3C Y was a guinea pig in a clinical study of medicine. |
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